NKIRAS1 Antibody (YA8400)
(Synonyms: kappaB-Ras1; KBRAS1)NKIRAS1 Antibody (YA8400) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NKIRAS1.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
NKIRAS1 Antibody (YA8400) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NKIRAS1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 21.5 kDa
Full length human recombinant protein of human NKIRAS1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NKIRAS1 is an Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q9NYS0: 192 amino acids, molecular weight 21643 Da.
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Subunit
Interacts with both NF-kappa-B inhibitor alpha (NFKBIA) and beta (NFKBIB) in vitro
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SwissProt ID
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Synonyms
kappaB-Ras1; KBRAS1
Documentation
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