NOX1 Antibody
(Synonyms: MOX1, NOH1, NOX1, NADPH oxidase 1, NOX-1, Mitogenic oxidase 1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1, MOX-1)NOX1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NOX1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
NOX1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NOX1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 64 kDa
Synthetic peptide corresponding to the center region of human NOX1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NOX1 is a NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor
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Subcellular Localization
Cell projection, invadopodium membrane; Cell membrane
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Expression
Tissue_Specificity: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. -
Isoforms & Post-Translational Modification
NOX1 has 2 isoforms, Q9Y5S8-1: amino acid length is 564, molecular weight is 64871 Da (predicted); Q9Y5S8-3: amino acid length is 515, molecular weight is 58972 Da (predicted).
Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity. -
Subunit
NOX1, NOXA1, NOXO1, RAC1 and CYBA forms a functional multimeric complex supporting reactive oxygen species (ROS) production.
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SwissProt ID
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Synonyms
MOX1, NOH1, NOX1, NADPH oxidase 1, NOX-1, Mitogenic oxidase 1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1, MOX-1
Documentation
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