Nucleoporin p62 Antibody (YA2997)
(Synonyms: IBSN; MGC841; NUP62; p62; SNDI)Nucleoporin p62 Antibody (YA2997) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nucleoporin p62.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
Nucleoporin p62 Antibody (YA2997) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nucleoporin p62.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 53 kDa
A synthesized peptide derived from human NUP62 aa481-522.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Nucleoporin p62 is essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown[1][2].
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Subcellular Localization
Nucleus, nuclear pore complex; Cytoplasm, cytoskeleton, spindle pole; Nucleus envelope; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
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Subunit
Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUP58 (By similarity). Interacts with NUP88 (PubMed:30543681).
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SwissProt ID
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Synonyms
IBSN; MGC841; NUP62; p62; SNDI
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Research Field
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Documentation
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