NUP50 Antibody (YA3126)(PBS only)

Cat. No.: HY-P83381A: Ficha de datos User Guide for Antibodies
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NUP50 Antibody (YA3126) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUP50.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

NUP50 Antibody (YA3126) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUP50.

Host

Rabbit

Peso molecular

Predicted band size: 50 kDa;

Observed band size: 50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UKX7

Gene ID

10762 [NCBI]

Immunogen

A synthetic peptide of human NUP50

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:200

Pureza	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008). Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity)

Subcellular Localization：Nucleus, nuclear pore complex; Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side

Expression：
Tissue_specificity:Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver

Isoforms & Post-Translational Modification：Q9UKX7 has 2 isomers: Q9UKX7-1: 50144 Da (predicted); Q9UKX7-2: 46863 Da (predicted).

Subunit：Interacts with Importin alpha-2, Importin beta, Importin beta-2, NUP153, Ran binding protein 7, CDKN1B and itself (By similarity).

Research Field

Synonyms

NPAP60; NPAP60L

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/cho-cell.html [Content Brief]