PAAF1 Antibody (YA8634)(PBS only)
(Synonyms: PAAF; Rpn14; WDR71)PAAF1 Antibody (YA8634) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PAAF1.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
PAAF1 Antibody (YA8634) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PAAF1.
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Host Mouse
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 42 kDa
Full length human recombinant protein of human PAAF1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation
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Expression
Tissue_Specificity: Ubiquitously expressed, with highest levels in kidney, brain and testis -
Isoforms & Post-Translational Modification
Q9BRP4 has three isomers: Q9BRP4-1: 42190 Da (predicted); Q9BRP4-2: 40439 Da (predicted); Q9BRP4-3: 29982 Da (predicted).
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Subunit
Interacts with PSMC1, PSMC2, PSMC3, PSMC4, PSMC5 and PSMC6
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SwissProt ID
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Synonyms
PAAF; Rpn14; WDR71
Documentation
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