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PARVB Antibody (YA8599)(PBS only)

(Synonyms: CGI-56)

PARVB Antibody (YA8599) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PARVB.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PARVB Antibody (YA8599)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

PARVB Antibody (YA8599) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PARVB.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 41.5 kDa
Immunogen

Full length human recombinant protein of human PARVB produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PARVB is an Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration

  • Subcellular Localization

    Cell junction, focal adhesion,Cell membrane,Cytoplasm, cytoskeleton,Cell projection, lamellipodium,Cytoplasm, myofibril, sarcomere,Cytoplasm, myofibril, sarcomere, Z line

  • Expression


    Tissue_Specificity: Expressed predominantly in heart and skeletal muscle

  • Isoforms & Post-Translational Modification

    Q9HBI1 has three isomers: Q9HBI1-1: 41714 Da (predicted); Q9HBI1-2: 45183 Da (predicted); Q9HBI1-3: 37538 Da (predicted).

  • Subunit

    Interacts with DYSF

  • SwissProt ID

    Q9HBI1

  • Synonyms

    CGI-56

PARVB Antibody (YA8599)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PARVB Antibody (YA8599)(PBS only) Product Image
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  • PARVB Antibody (YA8599)(PBS only) Product Image