Pax-4 Antibody (YA5008)
(Synonyms: PAX4; Paired box protein Pax-4)Pax-4 Antibody (YA5008) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Pax-4.
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Host:
Mouse
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
Pax-4 Antibody (YA5008) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Pax-4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 38 kDa;
Purified recombinant fragment of human Pax-4 expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Pax-4 plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
O43316 has 3 isomers: O43316-1: 37833 Da (predicted); O43316-2: 29820 Da (predicted); O43316-4: 37061 Da (predicted).
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SwissProt ID
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Synonyms
PAX4; Paired box protein Pax-4
Documentation