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  4. Phospho-GATA3 (Ser308) Antibody (YA2593)

Phospho-GATA3 (Ser308) Antibody (YA2593)

Cat. No.: HY-P82848
COA User Guide for Antibodies Technical Support

Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño Precio Stock Cantidad
10 μL En stock
50 μL En stock
100 μL En stock
250 μL   Obtener un presupuesto  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • Descripciòn

  • Referencias

Descripciòn

Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular
Predicted band size: 48 kDa;
Observed band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser308 of human GATA3

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Phosphorylated
Isotype IgG  
Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background
Function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages
Subcellular Localization:Nucleus
Expression:
Tissue_specificity:T cells and endothelial cells
Isoforms & Post-Translational Modification:P23771 has 2 isomers: P23771-1: 47916 Da (predicted); P23771-2: 48045 Da (predicted).
Subunit:Interacts with TBX21 ('Tyr-530' phosphorylated form)
Database
Research Field

Immunology

Synonyms
GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3
Documentación
Referencias
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Phospho-GATA3 (Ser308) Antibody (YA2593)
Cat. No.:
HY-P82848
Cantidad:
MCE Japan Authorized Agent: