Phospho-SMC1 (S957) Antibody (YA6724)

Cat. No.: HY-P87031: Fiche technique User Guide for Antibodies
FAQs
Technical Support

Phospho-SMC1 (S957) Antibody (YA6724) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-SMC1 (S957).

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

Phospho-SMC1 (S957) Antibody (YA6724) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-SMC1 (S957).

Host

Rabbit

Clonality

Recombinant,Monoclonal

Masse moléculaire

Predicted band size: 144 kDa;

Observed band size: 150 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8NDV3

Gene ID

27127 [NCBI]

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser957 of Human SMC1 aa 945-980 / 1233.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Pureté	affinity purified.	Conjugation	Non-conjugated
Modification	Phosphorylated	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity)

Subcellular Localization：Nucleus,Chromosome,Chromosome, centromere

Isoforms & Post-Translational Modification：Q8NDV3 has two isomers: Q8NDV3-3: 143789 Da (predicted); Q8NDV3-2: 135789 Da (predicted).

Subunit：Forms a heterodimer with SMC3

Synonyms

CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; Segregation of mitotic chromosomes like 1 antibody; SMC 1 antibody; SMC protein 1B antibody; SMC-1-beta antibody; SMC-1B antibody; SMC1 antibody; SMC1A antibody; SMC1alpha antibody; SMC1alpha protein antibody; SMC1B antibody; SMC1B_HUMAN antibody; SMC1BETA antibody; SMC1beta protein antibody; SMC1L1 antibody; SMC1L2 antibody; SMCB antibody; Structural maintenance of chromosome 1 like 1 protein antibody; Structural maintenance of chromosome 1 like 2 protein antibody; Structural maintenance of chromosomes 1A antibody; Structural maintenance of chromosomes 1B antibody; Structural maintenance of chromosomes protein 1B antibody;

Documentation

User Guide for Antibodies (1077 KB)