Phospho-SMC1 (S957) Antibody (YA6724)
(Synonyms: CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; Segregation of mitotic chromosomes like 1 antibody; SMC 1 antibody; SMC protein 1B antibody; SMC-1-beta antibody; SMC-1B antibody; SMC1 antibody; SMC1A antibody; SMC1alpha antibody; SMC1alpha protein antibody; SMC1B antibody; SMC1B_HUMAN antibody; SMC1BETA antibody; SMC1beta protein antibody; SMC1L1 antibody; SMC1L2 antibody; SMCB antibody; Structural maintenance of chromosome 1 like 1 protein antibody; Structural maintenance of chromosome 1 like 2 protein antibody; Structural maintenance of chromosomes 1A antibody; Structural maintenance of chromosomes 1B antibody; Structural maintenance of chromosomes protein 1B antibody; )Phospho-SMC1 (S957) Antibody (YA6724) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-SMC1 (S957).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-1:200 | 1:50-1:200 |
Product Details
Phospho-SMC1 (S957) Antibody (YA6724) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-SMC1 (S957).
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 150 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 144 kDa
Synthetic phospho-peptide corresponding to residues surrounding Ser957 of Human SMC1 aa 945-980 / 1233.
affinity purified.
Non-conjugated
Phosphorylated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SMC1 is a Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I
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Subcellular Localization
Nucleus,Chromosome,Chromosome, centromere
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Isoforms & Post-Translational Modification
Q8NDV3 has two isomers: Q8NDV3-3: 143789 Da (predicted); Q8NDV3-2: 135789 Da (predicted).
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Subunit
Forms a heterodimer with SMC3
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SwissProt ID
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Synonyms
CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; CDLS2 antibody; DKFZp686L19178 antibody; DXhXs423e antibody; DXS423E antibody; KIAA0178 antibody; MGC138332 antibody; OTTHUMP00000061876 antibody; RP6 29D12.1 antibody; SB1.8 antibody; Segregation of mitotic chromosomes 1 antibody; Segregation of mitotic chromosomes like 1 antibody; SMC 1 antibody; SMC protein 1B antibody; SMC-1-beta antibody; SMC-1B antibody; SMC1 antibody; SMC1A antibody; SMC1alpha antibody; SMC1alpha protein antibody; SMC1B antibody; SMC1B_HUMAN antibody; SMC1BETA antibody; SMC1beta protein antibody; SMC1L1 antibody; SMC1L2 antibody; SMCB antibody; Structural maintenance of chromosome 1 like 1 protein antibody; Structural maintenance of chromosome 1 like 2 protein antibody; Structural maintenance of chromosomes 1A antibody; Structural maintenance of chromosomes 1B antibody; Structural maintenance of chromosomes protein 1B antibody;
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