PKC eta Antibody

PKC eta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 78 kDa, targeting to PKC eta. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

PKC eta: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]

Free

5583

Predicted band size: 78 kDa

affinity purified

Non-conjugated

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Rabbit

Human, Mouse, Rat

P24723

WB: 1:500-1:1,000 ;IP: 1:20

WB, IP

Liquid

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Synthetic peptide corresponding to Human PKC eta.The exact sequence is proprietary to MCE.