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Cat. No.: HY-P87635

PRLR Antibody (YA7319)

PRLR Antibody (YA7319) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRLR.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:50-200	1:50-200	1:50-200	1:50-200

Description

PRLR Antibody (YA7319) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRLR.

Host Rabbit
Clonality Recombinant,Monoclonal
Observed Molecular Weight

Observed band size: 95 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 70 kDa

Immunogen

A synthesized peptide derived from human Prolactin receptor

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

PRLR is a This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling
Subcellular Localization

Membrane,Secreted
Expression

Tissue_Specificity: Expressed in breast, placenta, kidney, liver and pancreas
Isoforms & Post-Translational Modification

P16471 has 9 isomers: P16471-1: 69506 Da (predicted); P16471-2: 57953 Da (predicted); P16471-3: 26545 Da (predicted); P16471-4: 42639 Da (predicted); P16471-5: 39806 Da (predicted); P16471-6: 32760 Da (predicted); P16471-7: 30705 Da (predicted); P16471-8: 24773 Da (predicted); P16471-9: 35011 Da (predicted).
Subunit

Homodimer upon hormone binding
SwissProt ID

P16471