PSD93 Antibody
(Synonyms: DLG2, Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93)
Based on 1 Customer Validation
PSD93 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PSD93.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IF-Tissue, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:100-1:300 | 1:40000 | 1:50-200 |
Product Details
PSD93 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PSD93.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman, Mouse, Rat
The antiserum was produced against synthesized peptide derived from human DLG2. AA range:601-650
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PSD93 is required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity)
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Subcellular Localization
Cell membrane; Postsynaptic density; Synapse; Membrane; Cell projection, axon; Perikaryon
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Isoforms & Post-Translational Modification
PSD93 has 5 isoforms, Q15700-1: amino acid length is 870, molecular weight is 97552 Da (predicted); Q15700-2: amino acid length is 975, molecular weight is 109371 Da (predicted); Q15700-3: amino acid length is 749, molecular weight is 83405 Da (predicted); Q15700-4: amino acid length is 909, molecular weight is 100981 Da (predicted); Q15700-5: amino acid length is 334, molecular weight is 38404 Da (predicted).
Palmitoylation of isoform 1 is not required for targeting to postsynaptic density. -
Subunit
Interacts through its PDZ domains with NETO1 (By similarity).
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SwissProt ID
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Synonyms
DLG2, Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93
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