PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077)

製品番号: HY-P88393: データシート User Guide for Antibodies
FAQs
Technical Support

PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMB7 (Proteasome 20S beta 7 ).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMB7 (Proteasome 20S beta 7 ).

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 29.8 kDa

Species Reactivity

Human, Dog, Rat, Monkey, Mouse

SwissProt ID

Q99436

Immunogen

Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity

Subcellular Localization：Cytoplasm,Nucleus

Expression：
Tissue_Specificity: Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues

Isoforms & Post-Translational Modification：Q99436 has two isomers: Q99436-1: 29965 Da (predicted); Q99436-2: 15323 Da (predicted).

Subunit：The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits

Synonyms

ドキュメンテーション

User Guide for Antibodies (1077 KB)

PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

最近チェックした製品:

製品名

カスタマ需要量 *

お名前 *

タイトル

メールアドレス *

電話番号 *

デパートメント

組纖名 *

市区町村

都道府県

国或いは地域 *

必ず会社名を記載ください。個人への返信は行いません。

備考

製品名

Lot #

お名前 *

国或いは地域 *

メールアドレス *

備考

お名前
メール *

	Sorry, but the email address you supplied was invalid.

PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077)

Product Detail

Background

説明

PSMB7 (Proteasome 20S beta 7 ) Antibody (YA8077) 関連分類

最近チェックした製品:

Request for HNMR Report

Request for HNMR Report