SALL4 Antibody (YA5998)
Based on 1 Customer Validation
SALL4 Antibody (YA5998) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SALL4.
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Host:
Rabbit
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Isotype:
IgG/Kappa
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Application:
WB, ICC/IF, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 |
Product Details
SALL4 Antibody (YA5998) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SALL4.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 165 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 112 kDa
Protein A
Non-conjugated
Unmodified
IgG/Kappa
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SALL4 transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_specificity:It is expressed in the testes. It is constitutively expressed in acute myeloid leukemia (AML) . -
Isoforms & Post-Translational Modification
Q9UJQ4 has 2 isomers: Q9UJQ4-1: 112231 Da (predicted); Q9UJQ4-2: 65708 Da (predicted).
Isoform SALL4B exists primarily as a ubiquitinated form;Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4 -
Subunit
Interacts with POU5F1/OCT4 (PubMed:23012367). Interacts with NANOG (By similarity). Interacts with BEND3 (PubMed:21914818). Interacts with NSD2 (via PHD-type zinc fingers 1, 2 and 3) (By similarity). Interacts with NRBP1 (PubMed:22510880)
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SwissProt ID
Documentation
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Data Sheet (231 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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User Guide for Antibodies (1077 KB)