SAPAP1 Antibody (YA5055)
(Synonyms: DLGAP1; DAP1; GKAP; Disks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1)SAPAP1 Antibody (YA5055) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SAPAP1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, ELISA
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Reactivity :
Human
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Formulation:
Supplied in Ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:1000 | 1:10000 |
Product Details
SAPAP1 Antibody (YA5055) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SAPAP1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 109kDa;
Purified recombinant fragment of human GKAP expressed in E. Coli. The exact sequence is proprietary to MCE.
Endogenous
affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SAPAP1 is a Part of the postsynaptic scaffold in neuronal cells
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Subcellular Localization
Cell membrane; Peripheral membrane protein; Postsynaptic density; Synapse
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Expression
Tissue_specificity:Expressed in brain -
Isoforms & Post-Translational Modification
O14490 has 7 isomers: O14490-1: 108873 Da (predicted); O14490-2: 75261 Da (predicted); O14490-3: 69969 Da (predicted); O14490-4: 76159 Da (predicted); O14490-5: 74058 Da (predicted); O14490-6: 76245 Da (predicted); O14490-7: 103581 Da (predicted).
Ubiquitinated by TRIM3; leading to proteasomal degradation -
Subunit
Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1 (By similarity). Interacts with MPP2 (via the SH3-Guanylate kinase-like sub-module) (By similarity)
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SwissProt ID
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Synonyms
DLGAP1; DAP1; GKAP; Disks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1
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