SCARA5 Antibody
(Synonyms: UNQ2938/PRO28700, SCARA5, Scavenger receptor class A member 5, Scavenger receptor hlg)
Based on 1 Customer Validation
SCARA5 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to SCARA5.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-200 |
Product Details
SCARA5 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to SCARA5.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 54 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 53 kDa
Synthetic peptide corresponding to the C-terminal region of human SCARA5.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SCARA5 is a Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1)
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Subcellular Localization
Cell membrane
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Isoforms & Post-Translational Modification
SCARA5 has 4 isoforms, Q6ZMJ2-1: amino acid length is 495, molecular weight is 53994 Da (predicted); Q6ZMJ2-2: amino acid length is 400, molecular weight is 43293 Da (predicted); Q6ZMJ2-3: amino acid length is 357, molecular weight is 38702 Da (predicted); Q6ZMJ2-4: amino acid length is 270, molecular weight is 28871 Da (predicted).
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Subunit
Homotrimer
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SwissProt ID
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Synonyms
UNQ2938/PRO28700, SCARA5, Scavenger receptor class A member 5, Scavenger receptor hlg
Documentation
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