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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. SCARB1 Antibody (YA1160)

SCARB1 Antibody (YA1160)

Cat. No.: HY-P81415
User Guide for Antibodies Technical Support

SCARB1 Antibody (YA1160) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCARB1.

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사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 제품 설명

제품 설명

SCARB1 Antibody (YA1160) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCARB1.
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 61 kDa;
Observed band size: 80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant protein of human Scavenging Receptor SR-BI
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.209.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218); (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed:12356718, PubMed:12913001, PubMed:18000990). Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate (PubMed:12356718); (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus; (Microbial infection) Facilitates the entry of human coronavirus SARS-CoV-2 by acting as an entry cofactor through HDL binding
Subcellular Localization：Cell membrane; Multi-pass membrane protein; Membrane, caveola; Multi-pass membrane protein
Expression：
Tissue_specificity:Broad expression
Isoforms & Post-Translational Modification：Q8WTV0 has 5 isomers: Q8WTV0-1: 60878 Da (predicted); Q8WTV0-2: 56973 Da (predicted); Q8WTV0-3: 45103 Da (predicted); Q8WTV0-4: 53579 Da (predicted); Q8WTV0-5: 56170 Da (predicted).
N-glycosylated;The six cysteines of the extracellular domain are all involved in intramolecular disulfide bonds
Subunit：The C-terminal region binds to PDZK1
Database

Entrez Gene: 949 Human

SwissProt: Q8WTV0 Human

OMIM: 601040 Human

Research Field

Microbiology
Synonyms
CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; Scavenging Receptor SR-BI
각종 서류
User Guide for Antibodies (1077 KB)

SCARB1 Antibody (YA1160) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
SCARB1 Antibody (YA1160)
Cat. No.:
HY-P81415
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