SOD2 Antibody (YA5501)
(Synonyms: SOD2; Superoxide dismutase [Mn], mitochondrial)
Based on 1 Customer Validation
SOD2 Antibody (YA5501) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SOD2.
-
Host:
Mouse
-
Application:
WB, ICC/IF, ELISA
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:1000-5000 |
Product Details
SOD2 Antibody (YA5501) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SOD2.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 25 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 25 kDa
AA range: 1-222
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SOD2 is a Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems
-
Subcellular Localization
Mitochondrion matrix
-
Expression
Induction:Expression is regulated by KRIT1 -
Isoforms & Post-Translational Modification
P04179 has 4 isomers: P04179-1: 24750 Da (predicted); P04179-2: 20724 Da (predicted); P04179-3: 18262 Da (predicted); P04179-4: 19730 Da (predicted).
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity;Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity);Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability -
Subunit
Homotetramer
-
SwissProt ID
-
Synonyms
SOD2; Superoxide dismutase [Mn], mitochondrial
Documentation
Powered by Bioz
