1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. SOD2 Antibody (YA5501)

SOD2 Antibody (YA5501) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SOD2.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • Documentation

Description

SOD2 Antibody (YA5501) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SOD2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight
Predicted band size: 25 kDa;
Observed band size: 25 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

AA range: 1-222

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-500
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:1000-5000
Purity affinity chromatography. Conjugation Non-conjugated
Modification Unmodified  
Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background
Function:Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems
Subcellular Localization:Mitochondrion matrix
Expression:
Induction:Expression is regulated by KRIT1
Isoforms & Post-Translational Modification:P04179 has 4 isomers: P04179-1: 24750 Da (predicted); P04179-2: 20724 Da (predicted); P04179-3: 18262 Da (predicted); P04179-4: 19730 Da (predicted).
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity;Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity);Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability
Subunit:Homotetramer
Synonyms
SOD2; Superoxide dismutase [Mn], mitochondrial
Documentation

SOD2 Antibody (YA5501) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SOD2 Antibody (YA5501)
Cat. No.:
HY-P85809
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