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SPTBN1 Antibody (YA6108)

(Synonyms: SPTBN1; SPTB2; Spectrin beta chain; non-erythrocytic 1; Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1)
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SPTBN1 Antibody (YA6108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SPTBN1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG/Kappa

  • Application:

    WB, IHC-P, ICC/IF, ELISA

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Conjugation:
    Non-conjugated
  • SPTBN1 Antibody (YA6108) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:1000-1:5000 1:2000-1:10000 1:200-1:1000 1:5000-1:20000

Product Details

Description

SPTBN1 Antibody (YA6108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SPTBN1.

  • Host Rabbit
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 275 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 275 kDa
Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG/Kappa

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SPTBN1 is a Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function

  • Subcellular Localization

    Cytoplasm, cytoskeleton; Cytoplasm, myofibril, sarcomere, M line; Cytoplasm, cytosol; Cell membrane; Cell membrane; Peripheral membrane protein; Cytoplasmic side

  • Expression


    Tissue_specificity:Isoform 2 is present in brain, lung and kidney (at protein level)

  • Isoforms & Post-Translational Modification

    Q01082 has 3 isomers: Q01082-1: 274609 Da (predicted); Q01082-2: 253091 Da (predicted); Q01082-3: 251397 Da (predicted).

  • Subunit

    Interacts with CAMSAP1 (PubMed:24117850). Interacts with ANK2 (PubMed:15262991, PubMed:34211179).

  • SwissProt ID

    Q01082

  • Gene ID
    6711 [NCBI]
  • Synonyms

    SPTBN1; SPTB2; Spectrin beta chain; non-erythrocytic 1; Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1

SPTBN1 Antibody (YA6108) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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