Tenascin-C Antibody (YA7535)
(Synonyms: HXB, TNC, Tenascin, TN, Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, JI, Myotendinous antigen, Neuronectin, Tenascin-C, TN-C)
Based on 1 Customer Validation
Tenascin-C Antibody (YA7535) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Tenascin-C.
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Host:
Rabbit
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Isotype:
IgG,Kappa
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Application:
WB, IHC-P, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 |
Product Details
Tenascin-C Antibody (YA7535) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Tenascin-C.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 270 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 241 kDa
The exact sequence is proprietary to MCE.
Endogenous
Protein A affinity purified
Non-conjugated
Unmodified
IgG,Kappa
Product Properties
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Appearance
Solution
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Formulation
Supplied in PPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Tenascin-C is an Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells[1].
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Subcellular Localization
Secreted, extracellular space, extracellular matrix
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Expression
Tissue_Specificity: Detected in fibroblasts (at protein level) -
Isoforms & Post-Translational Modification
P24821 has 6 isomers: P24821-1: 240853 Da (predicted); P24821-2: 191373 Da (predicted); P24821-3: 201359 Da (predicted); P24821-4: 230867 Da (predicted); P24821-5: 181528 Da (predicted); P24821-6: 171360 Da (predicted).
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Subunit
Homohexamer; disulfide-linked
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SwissProt ID
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Synonyms
HXB, TNC, Tenascin, TN, Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, JI, Myotendinous antigen, Neuronectin, Tenascin-C, TN-C
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