Tim10/TIMM10 Antibody (YA9422)
(Synonyms: TIMM10, TIM10A, TIMM10A)Based on 1 Customer Validation
Tim10/TIMM10 Antibody (YA9422) is a Mouse-derived and non-conjugated IgM monoclonal antibody, targeting to Tim10/TIMM10.
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Host:
Mouse
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Isotype:
IgM
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Application:
WB, ICC/IF, IF-Tissue, IP, ELISA
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-500 | 1:50-500 | 1-2μg per 100-500μg Total protein | 1:50-3000 |
Product Details
Tim10/TIMM10 Antibody (YA9422) is a Mouse-derived and non-conjugated IgM monoclonal antibody, targeting to Tim10/TIMM10.
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Host Mouse
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Species Reactivityhuman
OMIM: 602251
A synthesized peptide derived from human Tim10/TIMM10.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgM
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
Tim10/TIMM10 is a Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space
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Subcellular Localization
Mitochondrion inner membrane
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Expression
Tissue_Specificity: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. -
Isoforms & Post-Translational Modification
Tim10/TIMM10 has an amino acid length of 90, molecular weight is 10333 Da.
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Subunit
Heterohexamer; composed of 3 copies of TIMM9 and 3 copies of TIMM10/TIM10A, named soluble 70 kDa complex.
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SwissProt ID
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Synonyms
TIMM10, TIM10A, TIMM10A
Documentation