TINF2 Antibody (YA2126)

製品番号: HY-P82381: データシート SDS COA User Guide for Antibodies
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TINF2 Antibody (YA2126) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TINF2.

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容量	価格（税別）	在庫状況	数量
無料サンプル		今すぐ申し込む
10 μL	$72	在庫あり	Estimated Time of Arrival: December 31
50 μL	$186	在庫あり	Estimated Time of Arrival: December 31
100 μL	$294	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

TINF2 Antibody (YA2126) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TINF2.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 50 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BSI4

Gene ID

26277 [NCBI]

Immunogen

A synthesized peptide derived from human Tin2 aa200-315/451.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix

Subcellular Localization：Nucleus; Chromosome, telomere; Nucleus matrix

Expression：
Tissue_specificity:Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas

Isoforms & Post-Translational Modification：Q9BSI4 has 3 isomers: Q9BSI4-1: 50023 Da (predicted); Q9BSI4-2: 39444 Da (predicted); Q9BSI4-3: 15434 Da (predicted).

Subunit：Monomer. Found in a complex with POT1; TERF1 and TNKS1. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Interacts with TERF1, TERF2 and ACD

RRID

AB_3104490

Database

Entrez Gene: 26277 Human ; 28113 Mouse ; 290232 Rat

SwissProt: Q9BSI4 Human ; Q9QXG9 Mouse ;

OMIM: 613990 Human

Research Field

Epigenetics and Nuclear Signaling

Synonyms

DKCA3; Tin 2; TIN2; TINF 2; Tinf2

ドキュメンテーション

Select Batch:

データシート (232 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/hela-cell.html [Content Brief]