SND1/P100 Antibody (YA5092)

Cat. No.: HY-P85400: Data Sheet User Guide for Antibodies
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SND1/P100 Antibody (YA5092) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SND1/P100.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SND1/P100 Antibody (YA5092) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SND1/P100.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 102 kDa;

Species Reactivity

Human

SwissProt ID

Q7KZF4

Gene ID

27044 [NCBI]

Immunogen

Purified recombinant fragment of TudorSN (aa361-485) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:18453631, PubMed:28546213). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213). Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934). Plays a role in PIM1 regulation of MYB activity (PubMed:9809063). Functions as a transcriptional coactivator for STAT5 (By similarity); (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2); (Microbial infection) Promotes SARS-CoV-2 RNA synthesis by binding to negative-sense RNA and the viral protein nsp9

Subcellular Localization：Cytoplasm; Nucleus; Melanosome

Expression：
Tissue_specificity:general expression

Subunit：Forms a ternary complex with STAT6 and POLR2A (PubMed:12234934). Associates with the RNA-induced silencing complex (RISC) (PubMed:14508492, PubMed:28546213). Interacts with the RISC components AGO2, FMR1 and TNRC6A (PubMed:14508492, PubMed:28546213). Interacts with GTF2E1 and GTF2E2 (PubMed:7651391). Interacts with PIM1 (PubMed:9809063). Interacts with STAT5 (By similarity). Interacts with SYT11 (via C2 2 domain); the interaction with SYT11 is direct (By similarity)

Synonyms

SND1; TDRD11; Staphylococcal nuclease domain-containing protein 1; 100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activator

Documentation

User Guide for Antibodies (1077 KB)