UBE2M Antibody (YA7797)(PBS only)
(Synonyms: hUbc12; UBC-RS2; UBC12)UBE2M Antibody (YA7797) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBE2M.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF
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Reactivity :
Human, Dog, Monkey, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-250 |
Product Details
UBE2M Antibody (YA7797) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to UBE2M.
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Host Mouse
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Species ReactivityHuman, Dog, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 20.7 kDa
Full length human recombinant protein of human UBE2M produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
UBE2M is an Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation
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Isoforms & Post-Translational Modification
P61081 has two isomers: P61081-1: 20900 Da (predicted); P61081-2: 24373 Da (predicted).
The acetylation of Met-1 increases affinity for DCUN1D1 by about 2 orders of magnitude and is crucial for NEDD8 transfer to cullins -
Subunit
Interacts with UBA3 and RBX1
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SwissProt ID
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Synonyms
hUbc12; UBC-RS2; UBC12
Documentation
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