VAPA Antibody (YA6914)

Cat. No.: HY-P87226: Data Sheet User Guide for Antibodies
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VAPA Antibody (YA6914) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAPA.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

VAPA Antibody (YA6914) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAPA.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size：28 kDa;

Observed band size: 28 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9P0L0

Immunogen

Recombinant protein within Human VAPA aa 1-100 / 249.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44 (PubMed:32344433, PubMed:33124732). STARD3-VAPA interaction enables cholesterol transfer from the ER to endosomes (PubMed:33124732). Via interaction with WDR44 participates in neosynthesized protein export (PubMed:32344433). In addition, recruited to the plasma membrane through OSBPL3 binding (PubMed:25447204). The OSBPL3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204). With OSBPL3, may regulate ER morphology (PubMed:16143324). May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470)

Subcellular Localization：Endoplasmic reticulum membrane,Cell membrane,Cell junction, tight junction,Nucleus membrane

Expression：
Tissue_Specificity: Ubiquitous

Isoforms & Post-Translational Modification：Q9P0L0 has two isomers: Q9P0L0-1: 27893 Da (predicted); Q9P0L0-2: 32614 Da (predicted).

Subunit：Homodimer; disulfide-linked (PubMed:11511104, PubMed:33124732)

Synonyms

33 kDa Vamp-associated protein antibody

각종 서류

User Guide for Antibodies (1077 KB)