Wnt2 Antibody
(Synonyms: Int 1 related protein, INT1L 1, INT1L1, IRP, IRP protein, ONCOGENE INT1 LIKE 1, Protein Wnt-2, Secreted growth factor, Wingless type MMTV integration site family member 2, WNT2)Wnt2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Wnt2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 |
Product Details
Wnt2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Wnt2.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 40 kDa;
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 40 kDa
Synthetic peptide of human WNT2
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Wnt2 is a Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity)[1].
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Subcellular Localization
Secreted, extracellular space, extracellular matrix; Secreted
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Expression
Tissue_Specificity: Expressed in brain in the thalamus, in fetal and adult lung and in placenta. -
Isoforms & Post-Translational Modification
Wnt2 has an amino acid length of 360, molecular weight is 40418 Da.
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. -
SwissProt ID
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Synonyms
Int 1 related protein, INT1L 1, INT1L1, IRP, IRP protein, ONCOGENE INT1 LIKE 1, Protein Wnt-2, Secreted growth factor, Wingless type MMTV integration site family member 2, WNT2
Documentation
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