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  5. XPF Antibody (YA7834)(PBS only)

XPF Antibody (YA7834)(PBS only)

Cat. No.: HY-P88150A
User Guide for Antibodies Technical Support

XPF Antibody (YA7834) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to XPF.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

XPF Antibody (YA7834) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to XPF.
Host

Mouse
Molecular Weight

Predicted band size: 104.3 kDa
Species Reactivity
Human, Mouse
SwissProt ID
Immunogen

Full length human recombinant protein of human XPF produced in HEK293 cell.
Application &
Dilution Ratio
Application Dilution Ratio
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
FC
FC: Flow Cytometry
1:100
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-800
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG2b  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair
Subcellular Localization：Nucleus,Chromosome
Isoforms & Post-Translational Modification：Q92889 has two isomers: Q92889-1: 104486 Da (predicted); Q92889-2: 42745 Da (predicted).
Acetylation at Lys-911 by KAT5 promotes interaction with ERCC1 by disrupting a salt bridge between Glu-907 and Lys-911, thereby exposing a second binding site for ERCC1 (PubMed:32034146)
Subunit：Heterodimer composed of ERCC1 and ERCC4/XPF (PubMed:10413517, PubMed:16076955, PubMed:16338413, PubMed:25538220, PubMed:32034146)
Synonyms
ERCC11; FANCQ; RAD1; XFEPS; XPF
Documentation
User Guide for Antibodies (1077 KB)

XPF Antibody (YA7834)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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XPF Antibody (YA7834)(PBS only)
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