Anticancer agent 254

Cat. No.: HY-119324 Purity: 95.62%: Data Sheet
COA

SDS
Handling Instructions
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Anticancer agent 254 (compound 10) is a dichloroacetic acid-loaded compound with enhanced antitumor activity against leukemia cells in vitro and better stability in vivo, and can be considered for preclinical evaluation of cancer inhibition.

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Anticancer agent 254 화학구조

CAS No. : 1841421-67-7

사이즈	재고	수량
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	견적 받기	Estimated Time of Arrival: December 31
10 mg	견적 받기
50 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	0.34 mM Compound: 10	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 26653539]
JVM-2	IC₅₀	0.41 mM Compound: 10	Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay	[PMID: 26653539]
Maver1	IC₅₀	0.55 mM Compound: 10	Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay	[PMID: 26653539]
PBMC	IC₅₀	1.26 mM Compound: 10	Cytotoxicity against human PBMC cells after 48 hrs by MTT assay Cytotoxicity against human PBMC cells after 48 hrs by MTT assay	[PMID: 26653539]

분자량

479.01

화학식

C₁₂H₁₈Cl₆N₄O₃

CAS No.

1841421-67-7

Appearance

Solid

Color

White to off-white

SMILES

ClC(C(NCCN(CCNC(C(Cl)Cl)=O)CCNC(C(Cl)Cl)=O)=O)Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Purity: 95.62%

Select Batch:

Data Sheet (265 KB) SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Design, Synthesis, and Biological Characterization of Novel Mitochondria Targeted Dichloroacetate-Loaded Compounds with Antileukemic Activity