ApoA-I mimetic peptide

Name: ApoA-I mimetic peptide
Brand: MedChemExpress
SKU: HY-P5282
Rating: 4.5 (1 reviews)

Cat. No.: HY-P5282 Pureza: 98.90%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
Technical Support

ApoA-I mimetic peptide is an ApoA-I mimetic peptide. ApoA-I mimetic peptide has good phosphatidylcholine: cholesterol acyltransferase (LCAT) activation activity. ApoA-I mimetic peptide can be used to synthesize peptide/lipid complexes. ApoA-I mimetic peptide can be used in atherosclerosis research. (The sequence is: PVLDLFRELLNELLEALKQKLK).

Para uso exclusivo en investigación. No vendemos a pacientes.

Síntesis de péptidos personalizados

ApoA-I mimetic peptide Estructura química

No. CAS : 221882-20-8

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

or Consulta para venta a granel

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Acyltransferase:

Ver todas las isoformas

ACAT1 ACAT2 MGAT2 ACAT DGAT1 DGAT2

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

In Vitro

ApoA-I mimetic peptide (1 mg/mL in synthetic HDL particles) increases NO production in human umbilical vein endothelial cells (HUVEC)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

2623.14

Fòrmula

C₁₂₂H₂₀₈N₃₀O₃₃

No. CAS

221882-20-8

Appearance

Solid

Color

White to off-white

Sequence

Pro-Val-Leu-Asp-Leu-Phe-Arg-Glu-Leu-Leu-Asn-Glu-Leu-Leu-Glu-Ala-Leu-Lys-Gln-Lys-Leu-Lys

Sequence Shortening

PVLDLFRELLNELLEALKQKLK

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvente y solubilidad

In Vitro:

H₂O : ≥ 100 mg/mL (38.12 mM)

DMSO : 10 mg/mL (3.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.3812 mL	1.9061 mL	3.8122 mL
5 mM	0.0762 mL	0.3812 mL	0.7624 mL
10 mM	0.0381 mL	0.1906 mL	0.3812 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 98.90%

Select Batch:

Ficha de datos (274 KB) SDS (252 KB)

COA (251 KB) RP-HPLC (255 KB) MS (219 KB) Elemental Analysis Report (109 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Helsingin yliopisto. Formation of therapeutic hdl-mimetic nanodiscs and their interaction with lecithin:cholesterol acyltransferase-a qcm study.

[2]. Emily E Morin, et al. Abstract 335: Atheroma-specific Delivery of Synthetic High-density Lipoprotein Containing Sphingosine-1-phosphate for Modulation of Vascular Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	0.3812 mL	1.9061 mL	3.8122 mL	9.5306 mL
H₂O	5 mM	0.0762 mL	0.3812 mL	0.7624 mL	1.9061 mL
	10 mM	0.0381 mL	0.1906 mL	0.3812 mL	0.9531 mL
	15 mM	0.0254 mL	0.1271 mL	0.2541 mL	0.6354 mL
	20 mM	0.0191 mL	0.0953 mL	0.1906 mL	0.4765 mL
	25 mM	0.0152 mL	0.0762 mL	0.1525 mL	0.3812 mL
	30 mM	0.0127 mL	0.0635 mL	0.1271 mL	0.3177 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.