1333170-15-2
1333170-15-2
Chemical Structure
(Rac)-DNDI-8219
- CAS. Nr.: 1333170-15-2
- Formula:C13H10F3N3O5
- Molecular Weight:345.23
IUPAC Name: 2-nitro-6-(4-(trifluoromethoxy)phenoxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
InChIKey: IXUWKDINJWESQG-UHFFFAOYSA-N
SMILES: FC(F)(F)OC1=CC=C(OC2CN3C(OC2)=NC([N+]([O-])=O)=C3)C=C1
Biological Activity: (Rac)-DNDI-8219 is an antituberculosis compound with potent anti-leishmanial activity. (Rac)-DNDI-8219 demonstrated superior efficacy in the Leishmania donovani mouse model. (Rac)-DNDI-8219 showed promising activity in the Leishmania infantum hamster model. (Rac)-DNDI-8219 candidate compound R-6 provided excellent oral efficacy in the same hamster model[1].
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(Rac)-DNDI-8219 | (Rac)-DNDI-8219 is an antituberculosis compound with potent anti-leishmanial activity. (Rac)-DNDI-8219 demonstrated superior efficacy in the Leishmania donovani mouse model. (Rac)-DNDI-8219 showed promising activity in the Leishmania infantum hamster model. (Rac)-DNDI-8219 candidate compound R-6 provided excellent oral efficacy in the same hamster model. | |||||||||||||||||||||
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