391210-00-7
391210-00-7
Chemical Structure
PD318088
- CAS. Nr.: 391210-00-7
- Formula:C16H13BrF3IN2O4
- Molecular Weight:561.09
IUPAC Name: 5-bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide
InChIKey: XXSSGBYXSKOLAM-UHFFFAOYSA-N
SMILES: BrC1=CC(C(NOCC(CO)O)=O)=C(C(F)=C1F)NC2=CC=C(C=C2F)I
Biological Activity: PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352 (HY-50295). PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research[1].
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PD318088 | 99.82% | PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352 (HY-50295). PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research. | ||||||||||||||||||||
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