52168-48-6
52168-48-6
Chemical Structure
Triacetonamine-d17
Synonym(s): 2,2,6,6-Tetramethyl-4-piperidone-d17
- CAS. Nr.: 52168-48-6
- Formula:C9D17NO
- Molecular Weight:172.34
IUPAC Name: 2,2,6,6-tetrakis(methyl-d3)piperidin-4-one-1,3,3,5,5-d5
InChIKey: JWUXJYZVKZKLTJ-PAVRUKQSSA-N
SMILES: [2H]C([2H])([2H])C1(N([2H])C(C([2H])([2H])[2H])(C([2H])([2H])C(C1([2H])[2H])=O)C([2H])([2H])[2H])C([2H])([2H])[2H]
Biological Activity: Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Triacetonamine-d17 | 99.93% | Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats. | ||||||||||||||||||||
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Triacetonamine | 99.96% | Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5. [Content Brief]
- [3]. Ting Jiang, et al. Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. Tissue Eng Regen Med. 2022 Apr;19(2):403-415. [Content Brief]
