5335-14-8
5335-14-8
Chemical Structure
NSC-2888
- CAS. Nr.: 5335-14-8
- Formula:C8H18O2S2
- Molecular Weight:210.36
InChIKey: IMUKMTAMDNNXIV-UHFFFAOYSA-N
SMILES: OCCSCCC(C)SCCO
Biological Activity: NSC-2888 is a Rho kinase II (ROCK-II) inhibitor with an IC50 of 8.4 nM against human targets. NSC-2888 inhibits enzymatic activity by binding to active site amino acids via hydrogen bonds and hydrophobic interactions. NSC-2888 induces relaxation of pre-contracted rat aortic strips. NSC-2888 can be used in research related to hypertension[1].
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NSC-2888 | NSC-2888 is a Rho kinase II (ROCK-II) inhibitor with an IC50 of 8.4 nM against human targets. NSC-2888 inhibits enzymatic activity by binding to active site amino acids via hydrogen bonds and hydrophobic interactions. NSC-2888 induces relaxation of pre-contracted rat aortic strips. NSC-2888 can be used in research related to hypertension. | |||||||||||||||||||||
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