DMHAPC-Chol
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA.
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- CAS. Nr.: 774598-29-7
- Formel: C35H63IN2O3
- Molecular Weight:686.79
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Chemical Information
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CAS. Nr. 774598-29-7
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Molecular Weight 686.79
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Formel C35H63IN2O3
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SMILES
C[C@@H]([C@]1(CC[C@]2([C@@]3(CC=C4C[C@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)OC(NCCC[N+](C)(CCO)C)=O)[H])[H])[H])CCCC(C)C.[I-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
Reinheit & Dokumentation
Verweise
[1]. A Percot. et al. A hydroxyethylated cholesterol-based cationic lipid for DNA delivery: effect of conditioning. Int J Pharm. 2004 Jun 18;278(1):143-63. [Content Brief]
[2]. Dominique Briane, et al. Inhibition of VEGF expression in A431 and MDA-MB-231 tumour cells by cationic lipid-mediated siRNA delivery. J Drug Target. 2012 May;20(4):347-54. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DMHAPC-Chol Related Classifications
HY-125734 Related Classifications
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