2934738-41-5
2934738-41-5
Chemical Structure
Antileishmanial agent-16
- CAS No.: 2934738-41-5
- Formula:C27H37N5O4
- Molecular Weight:495.61
IUPAC Name: 7-butoxy-2-oxo-N-(6-(4-(pyrrolidin-1-ylmethyl)-1H-1,2,3-triazol-1-yl)hexyl)-2H-chromene-3-carboxamide
InChIKey: XQYUJCAFCYPTOE-UHFFFAOYSA-N
SMILES: CCCCOC1=CC2=C(C=C(C(O2)=O)C(NCCCCCCN3C=C(N=N3)CN4CCCC4)=O)C=C1
Biological Activity: Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells)[1].
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Antileishmanial agent-16 | Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells). | |||||||||||||||||||||
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