Silicon dioxide
Based on 2 publication(s) in Google Scholar
Silicon dioxide (Silica) is the core of gold-coated silica nanoparticles. Silicon dioxide has the characteristic of a spherical structure, with a layer of gold nanoparticles covering its surface. Silicon dioxide can be used as a coating material for quantum dots, enhancing their stability, reducing toxicity and improving hydrophilicity.
For research use only. We do not sell to patients.
- CAS No.: 7631-86-9
- Formula: O2Si
- Molecular Weight:60.08
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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Amorphous silicaPharmaceutical Excipient -
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PEG300Neutral Polymer
Publications Citing Use of MedChemExpress (MCE) Silicon dioxide
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Biological Activity
Description
In Vitro
Silicon dioxide-based nanoparticles (SiO₂NPs) are one of the most widely used nanomaterials, and are extensively applied in industries, cosmetics, and biomedical fields. However, SiO₂NPs can damage decidualization by disrupting the autophagy process, which may lead to embryo absorption [1].
Silicon dioxide-coated quantum dots, as a multifunctional nanoscale platform, can be used as fluorescent markers for in vitro detection, for biomolecular sensing, and for in vivo and in vitro imaging [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 7631-86-9
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Appearance Solid
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Molecular Weight 60.08
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Formula O2Si
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Color White to off-white
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SMILES
O=[Si]=O
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Synonyms
Silica; Colloidal anhydrous silica
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Initial Source
Arca subcrenata Lischke
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (2)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (416.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 16.6445 mL | 83.2224 mL | 166.4447 mL | 416.1118 mL |
| 5 mM | 3.3289 mL | 16.6445 mL | 33.2889 mL | 83.2224 mL | |
| 10 mM | 1.6644 mL | 8.3222 mL | 16.6445 mL | 41.6112 mL | |
| 15 mM | 1.1096 mL | 5.5482 mL | 11.0963 mL | 27.7408 mL | |
| 20 mM | 0.8322 mL | 4.1611 mL | 8.3222 mL | 20.8056 mL | |
| 25 mM | 0.6658 mL | 3.3289 mL | 6.6578 mL | 16.6445 mL | |
| 30 mM | 0.5548 mL | 2.7741 mL | 5.5482 mL | 13.8704 mL | |
| 40 mM | 0.4161 mL | 2.0806 mL | 4.1611 mL | 10.4028 mL | |
| 50 mM | 0.3329 mL | 1.6644 mL | 3.3289 mL | 8.3222 mL | |
| 60 mM | 0.2774 mL | 1.3870 mL | 2.7741 mL | 6.9352 mL | |
| 80 mM | 0.2081 mL | 1.0403 mL | 2.0806 mL | 5.2014 mL | |
| 100 mM | 0.1664 mL | 0.8322 mL | 1.6644 mL | 4.1611 mL |
Silicon dioxide Related Classifications
HY-W019831 Related Classifications
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