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  4. AZ-PFKFB3-67 quarterhydrate

AZ-PFKFB3-67 quarterhydrate 

Cat. No.: HY-101972A Purity: ≥99.0%
COA Handling Instructions

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AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively.

For research use only. We do not sell to patients.

AZ-PFKFB3-67 quarterhydrate Chemical Structure

AZ-PFKFB3-67 quarterhydrate Chemical Structure

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AZ-PFKFB3-67 quarterhydrate Related Antibodies

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Description

AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively[1].

IC50 & Target

IC50: 11 nM (PFKFB3), 159 nM (PFKFB2), 1130 nM (PFKFB1)[1]
Molecular Weight

460.01

Formula

C26H25N5O3.1/4H2O
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1NCCC1)NC2=CC=C(OC3=CC4=C(N(CC5=C(C)ON=C5C)C=C4C#N)C=C3)C=C2.O.[1/4]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (251 KB) Elemental Analysis Report (109 KB)

Handling Instructions (2659 KB)
References
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AZ-PFKFB3-67 quarterhydrate Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ-PFKFB3-67 quarterhydrateOthersselectivemetabolicisoformPFKFBInhibitorinhibitorinhibit

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AZ-PFKFB3-67 quarterhydrate
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