AZ-PFKFB3-67 quarterhydrate
Based on 1 publication(s) in Google Scholar
AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively.
For research use only. We do not sell to patients.
- Purity: 99.0%
- Formula: C26H25N5O3.1/4H2O
- Molecular Weight:460.01
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) AZ-PFKFB3-67 quarterhydrate
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Biological Activity
IC50: 11 nM (PFKFB3), 159 nM (PFKFB2), 1130 nM (PFKFB1)[1]
Chemical Information
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Appearance Solid
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Molecular Weight 460.01
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Formula C26H25N5O3.1/4H2O
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Color White to off-white
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SMILES
O=C([C@H]1NCCC1)NC2=CC=C(OC3=CC4=C(N(CC5=C(C)ON=C5C)C=C4C#N)C=C3)C=C2.O.[1/4]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Cancer
B7-H3 suppresses CD8+ T cell immunologic function through reprogramming glycolytic metabolism. [Abstract]2024 Mar 11;15(9):2505-2517. PMID: 38577598
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AZ-PFKFB3-67 quarterhydrate Related Classifications
HY-101972A Related Classifications
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