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  4. BAY-771

BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux). BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism.

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BAY-771

BAY-771 화학구조

CAS No. : 2771756-82-0

사이즈 가격 재고 수량
1 mg 견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
5 mg 견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
10 mg 견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
25 mg 견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
50 mg   견적 받기  
100 mg   견적 받기  
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BAY-771 Related Antibodies

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제품 설명

BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux). BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism[1].

Cellular Effect
Cell Line Type Value Description References
U-87MG ATCC IC50
6200 nM
Compound: 43; BAY-771
Upregulation of BCAA expression in human U-87 MG cells
Upregulation of BCAA expression in human U-87 MG cells
[PMID: 36261130]
분자량

412.36

화학식

C22H15F3N2O3
CAS No.
SMILES

O=C1NC(C(F)(F)F)=CC(N1C2=CC(OC3=C(C)C=CC=C3)=CC4=C2C=CC=C4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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BAY-771 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-7712771756-82-0BAY771BAY 771Fluorescent Dyebranched-chain amino acid transaminases (BCATs)branched-chain amino acids (BCAAs)tumor metabolismInhibitorinhibitorinhibit

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상품명:
BAY-771
Cat. No.:
HY-156965
수량:
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