BCN-sulfamoyl-PEG2-sulfamoyl-bis(Val-Cit-PAB-Exatecan)
Based on 1 Customer Validation
BCN-sulfamoyl-PEG2-sulfamoyl-bis(Val-Cit-PAB-Exatecan) (compound 1b) is a conjugate composed of Exatecan (HY-13631) and an ADC linker (HY-183536).
For research use only. We do not sell to patients.
- Purity : 97.85%
- CAS No.: 2765424-52-8
- Formula: C108H128F2N20O31S2
- Molecular Weight:2304.41
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 2765424-52-8
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Appearance Solid
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Molecular Weight 2304.41
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Formula C108H128F2N20O31S2
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Color White to off-white
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SMILES
O=C1N2C(C3=NC4=CC(F)=C(C)C(CC5)=C4C([C@H]5NC(OCC(C=C6)=CC=C6NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCN(S(NC(OCCOCCNS(NC(OC[C@@H]7[C@@]8([H])[C@]7([H])CCC#CCC8)=O)(=O)=O)=O)(=O)=O)CCOC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C9)=CC=C9COC(N[C@@H]%10C%11=C%12C(C(N%13C%12)=CC([C@](O)(C(OC%14)=O)CC)=C%14C%13=O)=NC%15=CC(F)=C(C)C(CC%10)=C%15%11)=O)=O)=O)=O)=O)=O)=O)=O)=C3C2)=CC([C@](O)%16CC)=C1COC%16=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (43.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (284 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4340 mL | 2.1698 mL | 4.3395 mL | 10.8488 mL |
| 5 mM | 0.0868 mL | 0.4340 mL | 0.8679 mL | 2.1698 mL | |
| 10 mM | 0.0434 mL | 0.2170 mL | 0.4340 mL | 1.0849 mL | |
| 15 mM | 0.0289 mL | 0.1447 mL | 0.2893 mL | 0.7233 mL | |
| 20 mM | 0.0217 mL | 0.1085 mL | 0.2170 mL | 0.5424 mL | |
| 25 mM | 0.0174 mL | 0.0868 mL | 0.1736 mL | 0.4340 mL | |
| 30 mM | 0.0145 mL | 0.0723 mL | 0.1447 mL | 0.3616 mL | |
| 40 mM | 0.0108 mL | 0.0542 mL | 0.1085 mL | 0.2712 mL |
BCN-sulfamoyl-PEG2-sulfamoyl-bis(Val-Cit-PAB-Exatecan) Related Classifications
HY-W947216 Related Classifications
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