Benzethonium-d7 chloride
Based on 1 Customer Validation
Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.
For research use only. We do not sell to patients.
- Purity: 98.64%
- Formula: C27H35D7ClNO2
- Molecular Weight:455.12
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 121-54-0
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Appearance Solid
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Molecular Weight 455.12
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Formula C27H35D7ClNO2
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Color White to light yellow
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SMILES
CC(C)(C)CC(C1=CC=C(OCCOCC[N+](C)(C)C([2H])([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C=C1)(C)C.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 33.33 mg/mL (73.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 20 mg/mL (43.94 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.1972 mL | 10.9861 mL | 21.9722 mL | 54.9306 mL |
| 5 mM | 0.4394 mL | 2.1972 mL | 4.3944 mL | 10.9861 mL | |
| 10 mM | 0.2197 mL | 1.0986 mL | 2.1972 mL | 5.4931 mL | |
| 15 mM | 0.1465 mL | 0.7324 mL | 1.4648 mL | 3.6620 mL | |
| 20 mM | 0.1099 mL | 0.5493 mL | 1.0986 mL | 2.7465 mL | |
| 25 mM | 0.0879 mL | 0.4394 mL | 0.8789 mL | 2.1972 mL | |
| 30 mM | 0.0732 mL | 0.3662 mL | 0.7324 mL | 1.8310 mL | |
| 40 mM | 0.0549 mL | 0.2747 mL | 0.5493 mL | 1.3733 mL | |
| DMSO | 50 mM | 0.0439 mL | 0.2197 mL | 0.4394 mL | 1.0986 mL |
| 60 mM | 0.0366 mL | 0.1831 mL | 0.3662 mL | 0.9155 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.