2. Membrane Transporter/Ion Channel
  3. ATP Synthase
  4. BMS-199264

BMS-199264 is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 μM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 also enhances the recovery of contractile function following reperfusion.

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BMS-199264

BMS-199264 Estructura química

No. CAS : 675833-20-2

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Descripciòn

BMS-199264 is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 μM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 also enhances the recovery of contractile function following reperfusion[1].

Peso molecular

531.07

Fòrmula

C26H31ClN4O4S
No. CAS
SMILES

O[C@@H]1C(C)(OC2=CC=C(C=C2[C@H]1N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)S(=O)(N5CCCCC5)=O)C
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BMS-199264 Related Classifications

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Keywords:

BMS-199264675833-20-2BMS199264BMS 199264ATP Synthasecardiac necrosisischemiareperfusionF1F0 ATP hydrolaseInhibitorinhibitorinhibit

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BMS-199264
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