2. Neuronal Signaling
  3. AAK1
  4. BMS-901715

BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM.

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BMS-901715

BMS-901715 Estructura química

No. CAS : 1699861-37-4

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BMS-901715 Related Antibodies

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Descripciòn

BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM[1][2].

IC50 & Target

IC50: 3.3 nM (Adapter protein-2 associated kinase 1 (AAK1))[2]
In Vitro

Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BMS-901715 Related Antibodies
Peso molecular

448.52

Fòrmula

C22H28N10O
No. CAS
SMILES

OC1=CC(C2=NN(C(C)C)N=N2)=CC(NC3=NC=NN4C3=C(CN5CCC(N)CC5)C=C4)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
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Referencias
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BMS-901715 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-9017151699861-37-4BMS901715BMS 901715AAK1Adaptor-associated Kinase 1AP2-associated kinase 1potentInhibitorinhibitorinhibit

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Nombre del producto:
BMS-901715
Cat. No.:
HY-117453
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