Boc-2-methylamino-ethylcarbamate hydrochloride
Based on 1 Customer Validation
Boc-2-methylamino-ethylcarbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 202207-79-2
- Formula: C8H19ClN2O2
- Molecular Weight:210.70
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E523 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 202207-79-2
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Appearance Solid
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Molecular Weight 210.70
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Formula C8H19ClN2O2
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SMILES
Cl.O=C(OC(C)(C)C)NCCNC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (474.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7461 mL | 23.7304 mL | 47.4608 mL | 118.6521 mL |
| 5 mM | 0.9492 mL | 4.7461 mL | 9.4922 mL | 23.7304 mL | |
| 10 mM | 0.4746 mL | 2.3730 mL | 4.7461 mL | 11.8652 mL | |
| 15 mM | 0.3164 mL | 1.5820 mL | 3.1641 mL | 7.9101 mL | |
| 20 mM | 0.2373 mL | 1.1865 mL | 2.3730 mL | 5.9326 mL | |
| 25 mM | 0.1898 mL | 0.9492 mL | 1.8984 mL | 4.7461 mL | |
| 30 mM | 0.1582 mL | 0.7910 mL | 1.5820 mL | 3.9551 mL | |
| 40 mM | 0.1187 mL | 0.5933 mL | 1.1865 mL | 2.9663 mL | |
| 50 mM | 0.0949 mL | 0.4746 mL | 0.9492 mL | 2.3730 mL | |
| 60 mM | 0.0791 mL | 0.3955 mL | 0.7910 mL | 1.9775 mL | |
| 80 mM | 0.0593 mL | 0.2966 mL | 0.5933 mL | 1.4832 mL | |
| 100 mM | 0.0475 mL | 0.2373 mL | 0.4746 mL | 1.1865 mL |
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