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Cat. No.: HY-137136

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Femopixant

Femopixant is a P2X3 and P2X2/3 receptor antagonist. Femopixant can be used for the research of pain.

For research use only. We do not sell to patients.

CAS No.: 2310392-52-8
Formula: C₁₄H₁₅N₅O
Molecular Weight:269.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Femopixant Chemical Structure

CAS No.: 2310392-52-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Femopixant is a P2X3 and P2X2/3 receptor antagonist. Femopixant can be used for the research of pain^[1].

IC₅₀ & Target

^[1]

P2X3 Receptor

0.085 μM (IC₅₀)

P2X2/3

0.154 μM (IC₅₀)

All P2X Receptor Isoforms :

In Vitro

Femopixant (Compound 66) (15 min) inhibits P2X3 and P2X2/3 receptors in embryonic kidney cells, with IC₅₀ values of 0.085 μM and 0.154 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2310392-52-8
Molecular Weight 269.30
Formula C₁₄H₁₅N₅O
SMILES

C#CC1=NC=C(C(C)C)C(OC2=CN=C(N)N=C2N)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhao, et al. P2x3 and/or p2x2/3 receptor antagonist, pharmaceutical composition comprising same, and use thereof. WO2019085916A1. WIPO (PCT). 2018-10-31.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Femopixant

All P2X Receptor Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Femopixant Related Classifications

HY-137136 Related Classifications

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