Ppm1a - protein phosphatase, Mg2+/Mn2+ dependent, 1A Gene

Also Known as Pp2c1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24666

Summary

Enables protein C-terminus binding activity and transmembrane transporter binding activity. Predicted to be involved in cellular protein modification process; positive regulation of transcription, DNA-templated; and regulation of signal transduction. Predicted to act upstream of or within cellular response to transforming growth factor beta stimulus; negative regulation of BMP signaling pathway; and positive regulation of protein export from nucleus. Located in neuron projection. Orthologous to human PPM1A (protein Phosphatase, Mg2+/Mn2+ dependent 1A). [provided by Alliance of Genome Resources, Apr 2022]

Ppm1a Products (1)

mRNA Protein Name
NM_017038.2 NP_058734.1 protein phosphatase 1A

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
16844074 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15728831 RGD
enables transmembrane transporter binding IDA
IDA: Inferred from direct assay
15728831 RGD
Cellular Component GO Annotation Evidence References Source
located in neuron projection IDA
IDA: Inferred from direct assay
15728831 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1A

  • IA

  • PP2C-alpha

  • protein phosphatase IA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164220 PPM1A-IN-1 Inhibitor 95.71% Unkown
HY-163782 SMIP-031 98.60% Unkown
HY-P10359A TAT-QFNP12 acetate Inhibitor 95.90% Unkown
HY-P10359 TAT-QFNP12 Inhibitor / Unkown
HY-RS10960 PPM1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17113 Ppm1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23558 Ppm1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppm1a NCBI NCBI:5494