PPM1A-IN-1
Based on 1 Customer Validation
PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis.
For research use only. We do not sell to patients.
- Purity: 95.71%
- CAS No.: 2919466-30-9
- Formula: C16H15BrFNO2
- Molecular Weight:352.20
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | CC50 |
>200 μM
Compound: SMIP-30
|
Cytotoxicity against human Caco-2 cells by resazurin dye based assay
Cytotoxicity against human Caco-2 cells by resazurin dye based assay
|
[PMID: 38958057] |
| THP-1 | CC50 |
94.81 μM
Compound: SMIP-30
|
Cytotoxicity against human THP-1 cells by resazurin dye based assay
Cytotoxicity against human THP-1 cells by resazurin dye based assay
|
[PMID: 38958057] |
Chemical Information
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CAS No. 2919466-30-9
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Appearance Solid
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Molecular Weight 352.20
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Formula C16H15BrFNO2
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Color Off-white to light yellow
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SMILES
FC1=CC2=C3C=CC(OC)=CC3=C[N+](CCO)=C2C=C1.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 20 mg/mL (56.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8393 mL | 14.1965 mL | 28.3930 mL | 70.9824 mL |
| 5 mM | 0.5679 mL | 2.8393 mL | 5.6786 mL | 14.1965 mL | |
| 10 mM | 0.2839 mL | 1.4196 mL | 2.8393 mL | 7.0982 mL | |
| 15 mM | 0.1893 mL | 0.9464 mL | 1.8929 mL | 4.7322 mL | |
| 20 mM | 0.1420 mL | 0.7098 mL | 1.4196 mL | 3.5491 mL | |
| 25 mM | 0.1136 mL | 0.5679 mL | 1.1357 mL | 2.8393 mL | |
| 30 mM | 0.0946 mL | 0.4732 mL | 0.9464 mL | 2.3661 mL | |
| 40 mM | 0.0710 mL | 0.3549 mL | 0.7098 mL | 1.7746 mL | |
| 50 mM | 0.0568 mL | 0.2839 mL | 0.5679 mL | 1.4196 mL |
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