Hyaluronic acid

Hyaluronic acid purchased from MedChemExpress. Usage Cited in: Oncogene. 2023 Oct;42(44):3221-3235. [Abstract]

Customer Validation
4T1 cells mixed with exogenous Hyaluronic acid (HA, 500 μg) were subcutaneously inoculated into BALB/c mice, the mice were sacrificed on the eighth day after tumor graft. Representative immunofluorescent images of HA (green) and Hoechst33342 (blue) in tumors (left, scale bar, 100 μm), and statistic result of the MFI of HA (right), n = 4. P values were calculated by two-tailed unpaired t tests. E-F, The MSCs supernatant react with increasing dose of DOX. The results showed that exogenous HA was effectively converted into increased intratumoral HA content when assayed on the eighth day after tumor implantation.

Hyaluronic acid purchased from MedChemExpress. Usage Cited in: J Chem Neuroanat. 2021 Nov:117:101996. [Abstract]

Customer Validation
Photomicrograph of the visual cortex in section following hyaluronic acid injection and caffeine treatment. C (control group) revealed a normal neuronal cells distribution pattern with distinct nuclei; HA (Hyaluronic acid group; 25 μL/kg; single injection at the unilateral corneoscleral limbus) revealed pyknotic and scanty distribution of neuronal cells. PHA (intervention group) revealed histological alteration when compared to control group. CAF (caffeine group; 20 mg/kg; i.p.; once daily for 7 days) revealed scantily distribution of normal neuronal cells. Stained with H&E, (Scale bar = 51 μm).

Hyaluronic acid purchased from MedChemExpress. Usage Cited in: J Chem Neuroanat. 2021 Nov:117:101996. [Abstract]

Customer Validation
Photomicrograph showing TNF-α in a rat glaucomatous visual cortex. C represents the control group; HA (Hyaluronic acid; 25 μL/kg; single injection at the unilateral corneoscleral limbus) represent the hyaluronic acid group; PHA represents the intervention group; CAF represent the caffeine group. The expressions of TNF-α, and the damaged cells were characterized by a deep brown precipitates, round and shrunken morphology. (Scale bar = 51 μm).

Hyaluronic acid purchased from MedChemExpress. Usage Cited in: J Chem Neuroanat. 2021 Nov:117:101996. [Abstract]

Customer Validation
Effect of Caffeine on the tumour necrosis factor in the LGB and visual cortex of HA (25 μL/kg; single injection at the unilateral corneoscleral limbus)-induced rat. A): Tunel assay immunoreactivity in the primary visual cortex. B): Tunel assay immunoreactivity in the Lateral geniculate nucleus (LGN). Data represented as mean ± S.E.M. (n = 4). C = Control, HA= Hyaluronic acid, PHA = Post treatment group, CAF = Caffeine.

Hyaluronic acid purchased from MedChemExpress. Usage Cited in: J Chem Neuroanat. 2021 Nov:117:101996. [Abstract]

Customer Validation
Tonopen measurements of IOP in rats with hyaluronic acid injection and caffeine treatment. The elevated IOP was observed in rats injected with hyaluronic acid compared to the control and caffeine group. The distinction between the control, CAF and HA (Hyaluronic acid group; 25 μL/kg; single injection at the unilateral corneoscleral limbus) group was statistically significant after 8 days of HA injection. Control (C); hyaluronic acid (HA); Post hyaluronic acid (PHA); Caffeine (CAF); Intraocular pressure (IOP) *P < 0.05 (P value = 0.0001).