Brenipatide
Based on 1 Customer Validation
Brenipatide (LY-3537031) is a dual glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptor agonist. Brenipatide can be used for the study of metabolic disorders, obesity and diabetes.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.29%
- CAS No.: 2408921-49-1
- Formule: C228H354N46O72
- Masse moléculaire:4891.52
-
Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Activité biologique
Description
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 2408921-49-1
-
Appearance Solid
-
Masse moléculaire 4891.52
-
Formule C228H354N46O72
-
Color White to light yellow
-
Synonyms
LY-3537031
-
Sequence
{d-Tyr}-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Leu(aMe)}-Leu-Asp-Lys-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-Ala-Gln-{Aib}-Glu-Phe-Ile-Glu-{Tyr(aMe)}-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
-
Sequence Shortening
{d-Tyr}-{Aib}-EGTFTSDYSI-{Leu(aMe)}-LDK-{K(AEEA-AEEA-γGlu-C20 diacid)}-AQ-{Aib}-EFIE-{Tyr(aMe)}-LIAGGPSSGAPPPS-NH2
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (20.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2044 mL | 1.0222 mL | 2.0444 mL | 5.1109 mL |
| 5 mM | 0.0409 mL | 0.2044 mL | 0.4089 mL | 1.0222 mL | |
| 10 mM | 0.0204 mL | 0.1022 mL | 0.2044 mL | 0.5111 mL | |
| 15 mM | 0.0136 mL | 0.0681 mL | 0.1363 mL | 0.3407 mL | |
| 20 mM | 0.0102 mL | 0.0511 mL | 0.1022 mL | 0.2555 mL |