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Zotresiran

Zotresiran is a siRNA targeted to xanthine dehydrogenase.

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  • Zotresiran Chemical Structure
    Zotresiran Chemical Structure
CAS No.: 2756821-85-7
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  • Zotresiran Chemical Structure
    Zotresiran Chemical Structure RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Um-Cm-Gm-(2'-deoxy-2'-fluoro)U-Um-Cm-Cm-Am-Um-Am-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)C-Um-Cm-Um-Gm-Am-sp-Gm-sp-Am), complex with RNA (Um-sp-Cm-sp-Am-Gm-Am-Gm-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Gm-Gm-Am-Am-Cm-Gm-Am-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1)
    1/16
  • RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Um-Cm-Gm-(2'-deoxy-2'-fluoro)U-Um-Cm-Cm-Am-Um-Am-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)C-Um-Cm-Um-Gm-Am-sp-Gm-sp-Am), complex with RNA (Um-sp-Cm-sp-Am-Gm-Am-Gm-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Gm-Gm-Am-Am-Cm-Gm-Am-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1)