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Calcium hydrogen phosphate dihydrate  (Synonyms: Calcium phosphate dihydrate)

Cat. No.: HY-Y0708 Purity: 99.0%
Handling Instructions Technical Support

Calcium hydrogen phosphate dihydrate (Calcium phosphate dihydrate) can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.

For research use only. We do not sell to patients.

Calcium hydrogen phosphate dihydrate

Calcium hydrogen phosphate dihydrate Chemical Structure

CAS No. : 7789-77-7

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Based on 1 publication(s) in Google Scholar

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Description

Calcium hydrogen phosphate dihydrate (Calcium phosphate dihydrate) can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

In Vitro

Calcium hydrogen phosphate dihydrate exhibits a low solubility in urine, which enables the easy precipitation and formation of crystals in urine, leading to kidney stones or bladder stones[2][3].
Calcium hydrogen phosphate dihydrate acts as the precursor of hydroxyapatite and participates in the bone formation process[3].
Calcium hydrogen phosphate dihydrate can be used as food additive in breakfast cereals, dog food, flour and noodles for calcium supplement[3].
Calcium hydrogen phosphate dihydrate can be used as a tablet disintegrant in drug preparations[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.09

Formula

CaH5O6P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Ca].O=P(O)(O)O.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

0.5 M HCl : 10 mg/mL (58.11 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8109 mL 29.0546 mL 58.1091 mL
5 mM 1.1622 mL 5.8109 mL 11.6218 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
0.5 M HCl 1 mM 5.8109 mL 29.0546 mL 58.1091 mL 145.2728 mL
5 mM 1.1622 mL 5.8109 mL 11.6218 mL 29.0546 mL
10 mM 0.5811 mL 2.9055 mL 5.8109 mL 14.5273 mL
15 mM 0.3874 mL 1.9370 mL 3.8739 mL 9.6849 mL
20 mM 0.2905 mL 1.4527 mL 2.9055 mL 7.2636 mL
25 mM 0.2324 mL 1.1622 mL 2.3244 mL 5.8109 mL
30 mM 0.1937 mL 0.9685 mL 1.9370 mL 4.8424 mL
40 mM 0.1453 mL 0.7264 mL 1.4527 mL 3.6318 mL
50 mM 0.1162 mL 0.5811 mL 1.1622 mL 2.9055 mL
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Calcium hydrogen phosphate dihydrate Related Classifications

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